THE USE OF DENOSUMAB IN GIANT CELL TUMORS IN THE SACRUM

THE USE OF DENOSUMAB IN GIANT CELL TUMORS IN THE SACRUM

ABSTRACT Giant Cell Tumor (GCT), a benign tumor with local aggression, corresponds to 5% of primary tumors.Fifteen percent of these are located in the sacrum.En bloc resection is an effective treatment, but when it cannot be performed, Denosumab may be indicated as an alternative treatment.The objectives of this work are: to justify the indication;

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Hydrophobic solution functions as a multifaceted mosquito repellent by enhancing chemical transfer, altering object tracking, and forming aversive memory

Abstract Developing a safe and potent repellent of mosquitoes applicable to human skins is an effective measure against the spread of mosquito-borne diseases.Recently, we Sailing Bib Trousers have identified that hydrophobic solutions such as low viscosity polydimethylsiloxane (L-PDMS) spread on a human skin prevent mosquitoes from staying on and b

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Direct interaction of avermectin with epidermal growth factor receptor mediates the penetration resistance in Drosophila larvae

With the widespread use of avermectins (AVMs) for managing parasitic and agricultural pests, the resistance of Faber Daisy B EG6 A55 55cm Angled Cooker Hood Black Glass 330.0529.064 worms and insects to AVMs has emerged as a serious threat to human health and agriculture worldwide.The reduced penetration of AVMs is one of the main reasons for the d

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Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunctionResearch in context

Background: Preeclampsia is a major complication of pregnancy with no medical treatment.It is associated with placental oxidative stress, hypoxia and inflammation leading to soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion and reduced placental growth factor (PlGF).This results in widespread endothelial dysfunction

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